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Nos publications

  • Bayet K., Siffi Y. Gandolfini M.P., Lévy M. et Palantar A. : One-day hospitalization in oral surgery : a 2-year comparative study, Med. buccale Chir. buccale, (août 2017).

 Abstract: The increasing number of cardiovascular and/or neurological patients with polypathologic background has let practitioner to adapt the technical platform. The objective is to evaluate the indication of one day hospitalization (ODH) in oral surgery set up in 2013 in the Max Fourestier hospital (Nanterre)

  • Lévêque C, Lemahieu JC, Boughida C, Hassin J. : Funeral practice and demographic characteristics of people living in extreme poverty : Experience of the centre d’accueil et de soins hospitaliers of Nanterre, Prise en charge funéraire et caractéristiques démographiques des personnes en grande précarité, médecine palliative- soins de support- accompagnement- éthique (2014) [Article in French].
  • Cousin E., Le Gal D., Hassin J, : Epidémiologie de la population accueillie au CASH de Nanterre (Consultation médicale du CHAPSA, LHSS, SSIAD du CHRS-LD et CHRS), février 2014, [Article in French].

Résumé : Que ce soit au niveau de l’autonomie, des déficiences, de la dépendance, du handicap, du risque encouru et des soins tant médicaux que soignants on voit que ces personnes très  majoritairement âgées de moins de 60 ans ne pourront pas être accueillies dans des structures extérieures. L’évolution fréquente et inéluctable vers des démences de type alcoolique ou vasculaire de cette population est avérée. La prise en charge globale de ces patients nécessite un suivi médical, psychiatrique, social, en alcoologie et soignant.

  • Collectif des morts de la rue : Projet dénombrer et décrire : Améliore l’exhaustivité et la description des personnes « sans domicile fixe » décédées en France en 2013, Rapport final août 2014.

 Participation du Dr Jacques Hassin : « Pour l’Ile-de-France, l’état de santé est mieux renseigné pour les personnes dont le décès a été signalé par le CHAPSA de Nanterre » [Article in French].

  • Declerck P., Duprat P., Galonde O et Hassin J. : L’état médico-social et psychopathologique des personnes S.D.F, Etude réalisée à l’Antenne médico-sociale du Centre d’Accueil et de Soins Hospitaliers de Nanterre sur 276 personnes avec l’appui méthodologique de l’Ecole Nationale de Santé Publique Réseau National de santé publique. Il portait sur une file active de 300 personnes SDF (février 1996),[Article in French].

 Résumé : On ne peut pas vraiment parler de spécificité pathologique affectant les personnes sans-abri. La morbidité ajoutée peut être rapportée à deux explications : D’une part les conditions de vie dans la rue et d’autre part l’alcoolomanie et le tabagisme. Par ailleurs, cette étude montre que les hypothermies, les gelures et les « pieds de vagabond » qui semblaient être une pathologie très importante et spécifique du S. D. F., minorent très probablement leur importance, et ne représentent en tout cas pas les traits pathologiques essentiels. L’incidence de la pathologie psychiatrique que l’on sait importante est probablement sous-évaluée par la plupart des auteurs. L’incidence de la tuberculose est très importante, puisque nous avons dans cette étude dépisté 10 nouveaux cas sur 276 patients à l’occasion de 357 consultations en 9 mois. Cependant les affirmations alarmistes concernant une résurgence massive de la tuberculose chez les personnes S. D. F. ne traduisent pas un phénomène nouveau. Surtout est impossible d’envisager une approche de ces populations qui ne soit pas multidisciplinaire. Les problèmes médicaux, sociaux et psychopathologiques semblent tellement intriqués qu’on voit mal comment traiter autrement et de façon isolée ces problèmes médico-sociaux.

  • Charlier P, Déo S. : The notion of soul and its implications in medical biology, La notion d’âme et son implication en biologie médicale, Ethique, medicine and public health, Sous presse (2018).
  • Charlier P, Bou Abdallah F, Brun L, Hoang-Oppermann V, Deo S, Mostefai-Dulac Y, Mamzer MF, Hervé C. : The myth of virgin cleansing: Latest news on an archaic magico-religious practice, Ann Dermatol Venereol. (2018 Mar.)

Abstract: In the medical anthropology section of the Nanterre Hospital (France) for migrants and refugees, three cases were recorded of "virgin cleansing" in sub-Saharan African countries.

  • Charlier P, Bou Abdallah F.; Is penitentiary medicine a free medicine (French experience)? An open letter to the new general director of WHO, Eur. J. Intern. Med. (2017 Oct.).

Abstract: As a result of the current exponentially growing refugee population from the Middle-East and East Africa (Sudan, Darfur, Eritrea), clinicians (including forensic pathologists) are seeing atypical skin lesions, mainly of a traumatic nature, but in some cases associated with long-standing lesions related to ethnic practices.

  • Charlier P, Bou Abdallah F, Deo S.: Not a so peaceful end: Could adult death during sleep be due to hyper-adrenergic mechanism? Med Hypotheses (2017 Jul 6).
  • Bianucci R, Charlier P, Perciaccante A, Lippi D, Appenzeller O: The "Ulysses syndrome": An eponym identifies a psychosomatic disorder in modern migrants, Eur. J. Intern Med. (2017 Jun.).

Abstract: Due to civil wars, violence and persecutions, between 2015 and 2016, more than 1.4 million people, from the Middle East and Africa, fled their counties and migrated to Europe. The vast majority of migrants, who have already experienced enormous level of stressors, are faced with dangerous, often lethal, migratory journeys. Those who survive are exposed to adaptation stressors such as different languages, isolation, lack of work opportunities, diminished social status and a sense of failure in the new countries of residence. These are stressors that go far beyond the usual adaptation stresses to new cultures and migrants experience permanent crises with an imminent risk of developing the "Ulysses syndrome". As a consequence, many individuals often develop symptoms such as irritability, nervousness, migraine, tension headache, insomnia, tiredness, fear, loss of appetite and generalized ill-defined discomfort. If left untreated these symptoms, originally described by Hofer in the 17th century, may degenerate into a severe psychosomatic disorder leading to reactive depression. Here we expand the concept of Ulysses' syndrome and illustrate new initiatives aimed at reducing the level of stressors in migrants and at promoting their successful integration in their new countrie.

  • Charlier P, Bou Abdallah F, Mostefai Y, Brun L, Hervé C: Cutaneous lesions arising from Sudanese traditional medicine, Ann Dermatol. Venereol. (2017 May) [Article in French].
  • Charlier P. Medical anthropology consultations for refugees: Why are they necessary? Ann. Dermatol. Venereol. (2017 Feb) [Article in French].
  • Charlier P, Haroun A, Hervé C. Deliberate chemical dermatoglyphic burns in a political refugee, Brulures chimiques volontaires des empreintes digitales chez un réfugié politique Ann. Dermatol. Venereol. (2017 Feb.).
  • Charlier P, Weil R, Rainsard P, Poupon J, Brisard JC : The remains of Adolf Hitler: A biomedical analysis and definitive identification, Eur J Intern Med. (2018 May 17).
  • Stoeklé HC, Charlier P, Hervé C, Deleuze JF, Vogt G.: Artificial intelligence in internal medicine: Between science and pseudoscience, Eur. J. Intern. Med. (2018 May).
  • Perciaccante A, Charlier P, Negri C, Coralli A, Appenzeller O, Bianucci R.: Did Frédéric Chopin Die From Heart Failure?, J. Card. Fail, (5):342-344 (2018 May, 24).

Abstract: On October 17, 1849, Poland's greatest composer, Frédéric Chopin (1810-1849) died aged 39. His cause of death remains unknown. An investigation of the documental sources was performed to reconstruct the medical history of the artist. Since his earliest years, his life had been dominated by poor health. Recurrent episodes of cough, fever, headaches, lymphadenopathy- a series of symptoms that may be attributed to viral respiratory infections- manifested in his teens. Later in life, he had chest pain, hemoptysis, hematemesis, neuralgia, and arthralgia. Exhaustion and breathlessness characterized all his adult life. Coughing, choking, and edema of the legs and ankles manifested four months before his death. Several hypotheses ranging from cystic fibrosis to alpha-1 anti-trypsin deficiency and pulmonary tuberculosis have been proposed to explain Chopin's lifelong illness. We suggest that Chopin had dilated cardiomyopathy with consequent heart failure and cirrhosis that caused his death.

  • Charlier P, Benmoussa N, Froesch P, Huynh-Charlier I, Balzeau A.: Did Cro-Magnon 1 have neurofibromatosis type 1? Lancet Neuro, 3 91(10127) (Apr. 17 2018).
  • Charlier P, Appenzeller O, Deo S, Perciaccante A, Bianucci R. : Med Hypotheses. (2018 Apr).
  • Bianucci R, Appenzeller O, Evans P, Charlier P, Perciaccante A.: Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542-1591), Infection. (2018 Apr.)

Abstract: St. John of the Cross (1542-1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Here, an alternative diagnosis is proposed.

  • Benmoussa N, Hansen K, Charlier P. Hippocrates the otolaryngologist: an epidemiological analysis of ear-throat-nose diseases in the Corpus Hippocraticum. Acta Otolaryngol (2018 Mar).

Abstract: Hippocrates, a Greek physician during the fifth century BC., is often considered the father of medicine. The Corpus Hippocraticum comprising of 58 volumes was attributed to him alone for a long time. Nowadays, it is considered that several authors contributed to its creation between 450 and 150 BC., so over a period of 300 years. The objective of our study was to develop a nosological classification of all passages treating head and neck diseases.

  • Charlier P, Augias A, Sansonetti P, Bon C, Kennedy S, Segurel L.: Importance of intestinal paleomicrobiome study for contemporaneous medical problematics, Med Sci. (2017 Nov.)

Abstract: Human gut microbiome composition and diversity increasingly appear as a reliable marker of human evolution within his environment, and of health and its alteration (concept of dysbiosis); as a matter of fact, it can be considered as a strong marker of the disease status of individuals. Thus, in retrospect, the capacity to profile the gut microbiome would offer a great opportunity to identify individual and societal changes to which ancient populations were exposed. A global and diachronic view of the gut microbiome evolution is necessary in order to highlight the potential role of environmental factors or human habits in this process. However, to make the most of its contribution, archaeo-microbiology should aim at being as exhaustive as possible, encompassing parasites which have likely played a major role in the development of the mammalian immune system, and viruses.

  • Charlier P, Deo S.: The Anna O. mystery: Hysteria or neuro-tuberculosis? J. Neurol. Sci. (2017 Oct. 15).
  • Perciaccante A, Charlier P, Appenzeller O. : The maid of the Bridal Room by Andrea Mantegna (1431–1506) shows evidence of hypopituitary dwarfism and neurofibromatosis type-1, Journal of neurological science, Volume 380, (September 15, 2017).
  • Perciaccante A, Coralli A, Charlier P, Appenzeller O, Bianucci R.: Marcel Proust's contacts with neurology, Did mistrust in doctors lead him to refuse life-saving therapies? J. Neurol Sci. (2017 Jul 15).
  • Charlier P, Deo S, Bianucci R, Perciaccante A. Was aneurysm rupture a frequent cause of death in past population? Med Hypotheses, (2017 Jun.).
  • Charlier P., Hervé C.: What new life for the Parisian (and European) anatomical and pathological collections? struggle for medical education. Clin Anat. (2017 May;30).
  • Charlier P, Deo S, Hervé C. Anonymous biomedical publications for security reason? An open letter to the ICJME. Eur. J. Intern. Med. (2017 Apr). [Article in French]
  • Charlier P, Perciaccante A, Bianucci R.: information: Oldest medical description of osteogenesis imperfecta (17th Century, France). Clin Anat. (2017 Mar).

Abstract: Osteogenesis imperfecta (OI), also known as Lobstein's syndrome or Vrolik's syndrome, comprises a heterogeneous group of rare genetic connective tissue disorders. It is characterized by increased bone fragility, low bone mass, and susceptibility to bone fractures of variable severity. Originally named "osteomalacia congenita," the condition was first medically described in a family by Ekman in 1778. Here, we report a 17th century medical account from France, which predates Eckman's doctoral dissertation by about a century. Medical analysis of this anatomical presentation indicates a precise diagnosis of Type I OI.

  • Charlier P, Coppens Y, Malaurie J, Brun L, Kepanga M, Hoang-Opermann V, Correa Calfin JA, Nuku G, Ushiga M, Schor XE, Deo S, Hassin J, Hervé C.: A new definition of health? An open letter of autochthonous peoples and medical anthropologists to the WHO., Eur J Intern Med. (2017 Jan).

Abstract : Currently, for many practitioners (hospital and liberals) and researchers (including public health), the WHO definition of health is outdated: first it seems more utopian than pragmatic; then, it proves unsuitable for a large part of the world population. There is clearly a need to refine this definition or propose additional criteria to be more relevant or discriminating. In this perspective, what can indigenous people offer in the elaboration of a new definition of health? In this article, leaders or representatives of autochthonous peoples, anthropologists and physicians from many cultural origins (Amazonia, Patagonia, Papua New-Guinea, Inuit, North-American Indian, sub-Saharan Africa, India, China, Melanesia and Polynesia) have tried to identify and explain several key concepts that WHO should reintegrate into its new definition of health: human equilibrium in nature, accepted spirituality and adaptation. On the sidelines of the application of COP21 decisions that should give back to man his place into the environment, autochthonous people leaders, anthropologists and MDs explain why these three concepts are fundamental and universal health determinants, and need to be included in a new WHO definition of health.

  • Benmoussa N, Kerner J, Josset P, Conan P, Charlier P.: , Eur Arch Otorhinolaryngol. (2017 Jan)

Abstract: Joseph Gensoul was a pioneer of ENT surgery. In 1827, he performed the first total maxillectomy on 17-year-old boy. His work inspired many surgeons, who were previously unwilling to remove maxillary tumours. A paleopathological study performed in the Dupuytren museum allowed us to identify a skull from the early 19th century, with a large maxillar tumour. There were indications that this skull was operated according to Gensoul's technique. The aim of this study is to confirm that this patient had, in fact, received this surgical treatment. This is a historical and descriptive paleopathological study of a skull of the early 19th century of Dupuytren Museum in Paris. The historical research was conducted in collaboration with the French Academy of Medicine and the Museum of Medicine History (Paris). Bones mark cut studies allowed us to confirm that the patient was operated according to the method described by Gensoul in his "Surgical letter" in 1833. Our historical research has allowed us to understand the perspectives of surgeons in the 19th century and the intellectual processes that led to this discovery. At a time when the robotization and industrialization dominate our art, it is interesting to look to our past, our origins, and our history. The study of ancient humans remains and allows us to understand the origin of our specialty and pay tribute to these pioneering surgeons. Their intellectual approach and boldness should be acknowledged and applauded, especially as it is also the key to our success.

  • Charlier P, Augias A, Jacqueline S, Benmoussa N, Huynh-Charlier I.: A biological history of cancer, Gynecol Obstet Fertil. (2016 Dec) [Article in French].
  • Perciaccante A, Charlier P, Coralli A, Bianucci R.: “There will be blood”. Differences in the pictorial representation of the arterial spurt of blood in Caravaggio and followers, Eur J Intern Med. (2016 Oct).
  • Charlier P, Deo S, Mamzer-Bruneel MF, Hervé C.: Ethical limits to biomedical publications? Eur J Intern Med. (2016 Sep.).